{"id":813,"date":"2025-03-24T17:04:31","date_gmt":"2025-03-24T15:04:31","guid":{"rendered":"https:\/\/evolutionandsecurity.com\/?p=813"},"modified":"2025-03-24T18:10:23","modified_gmt":"2025-03-24T16:10:23","slug":"why-does-mitochondrial-disruption-cost-so-much","status":"publish","type":"post","link":"https:\/\/evolutionandsecurity.com\/?p=813","title":{"rendered":"Why does mitochondrial disruption cost so much?"},"content":{"rendered":"<p lang=\"en-US\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-815 size-large\" src=\"https:\/\/evolutionandsecurity.com\/wp-content\/uploads\/2025\/03\/mitochondria-6474672_1280-1024x576.webp\" alt=\"\" width=\"1024\" height=\"576\" srcset=\"https:\/\/evolutionandsecurity.com\/wp-content\/uploads\/2025\/03\/mitochondria-6474672_1280-1024x576.webp 1024w, https:\/\/evolutionandsecurity.com\/wp-content\/uploads\/2025\/03\/mitochondria-6474672_1280-300x169.webp 300w, https:\/\/evolutionandsecurity.com\/wp-content\/uploads\/2025\/03\/mitochondria-6474672_1280-768x432.webp 768w, https:\/\/evolutionandsecurity.com\/wp-content\/uploads\/2025\/03\/mitochondria-6474672_1280.webp 1280w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/p>\n<p lang=\"en-US\">Photo: Mitochondrium, SkieTheAce, Pixabay<\/p>\n<p lang=\"en-US\"><strong><span style=\"color: #000000;\"><span style=\"font-family: Liberation Serif, serif;\"><span style=\"font-size: x-large;\">Does evolution know the paths of the past and future? That\u2019s possible according to new research published in ,,Cell\u201d. How? By tracking the transport of signals and nutrients inside a cell.<\/span><\/span><\/span><\/strong><\/p>\n<p><span style=\"color: #000000;\"><span style=\"font-family: Liberation Serif, serif;\"><span style=\"font-size: x-large;\"><span lang=\"en-US\">The mitochondrion is a cell organelle <\/span><span lang=\"en-US\">with a <\/span><span lang=\"en-US\">separate from the cell nucleus genetic material inherited only from a female line. The body serves as a powerhouse for cells enabling proper functioning of either specific cell lines forming organs or the whole organism. There are theories the organelle is a footprint of the origin of life and thus the tiniest and the most important proof of evolution.<\/span><\/span><\/span><\/span><\/p>\n<p><strong><span style=\"color: #000000;\"><span style=\"font-family: Liberation Serif, serif;\"><span style=\"font-size: x-large;\"><span lang=\"en-US\">Mysterial connection with life<\/span><\/span><\/span><\/span><\/strong><\/p>\n<p><span style=\"color: #000000;\"><span style=\"font-family: Liberation Serif, serif;\"><span style=\"font-size: x-large;\"><span lang=\"en-US\">How? Due to its constitution from a more primordial and prior organism which could have given the beginning of eukaryote cell shape and ingredients that all latter life contain<\/span><span lang=\"en-US\">s<\/span><span lang=\"en-US\"> in bodies including humans. <\/span><span lang=\"en-US\">But there is something more. Microtubules that emerged in <\/span><span lang=\"en-US\">prehistoric <\/span><span lang=\"en-US\">selected bodies and eukaryote cells are responsible for transport <\/span><span lang=\"en-US\">processes within the cell and, what <\/span><span lang=\"en-US\">is of<\/span><span lang=\"en-US\"> significant importance, <\/span><span lang=\"en-US\">the code they posses is in charge <\/span><span lang=\"en-US\">of<\/span><span lang=\"en-US\">\u00a0<\/span><span lang=\"en-US\">the segregation of chromosomes during cell division<\/span><span lang=\"en-US\">. <\/span><span lang=\"en-US\">Mistakes during this process <\/span><span lang=\"en-US\">called mitosis <\/span><span lang=\"en-US\">may b<\/span><span lang=\"en-US\">e<\/span><span lang=\"en-US\"> costly for health and <\/span><span lang=\"en-US\">threaten<\/span><span lang=\"en-US\"> life of the organism. <\/span><span lang=\"en-US\">Some of them we can cure nowadays dependently on how much harm and in which locatio<\/span><span lang=\"en-US\">n<\/span><span lang=\"en-US\"> occur<\/span><span lang=\"en-US\">r<\/span><span lang=\"en-US\">ed<\/span><span lang=\"en-US\">. Some of them remain impossible to fix or we can only alleviate the consequences of those mistakes. <\/span><\/span><\/span><\/span><\/p>\n<p><span style=\"color: #000000;\"><span style=\"font-family: Liberation Serif, serif;\"><span style=\"font-size: x-large;\"><span lang=\"en-US\">However, according to Swizterland-based scientists, the key is the cytoskeleton, an essential step in the evolution of eukaryote cells. And these are microtubules and tubuline proteins enabling action that, among all keep the cell organelles in dedicated locations within the structure. What\u2019s fascinating the key to ensuring the stable functioning of the entire machinery is an adequate and stable binding of adenosine-triphosphate, a chemical energy that is then absorbed by microtubules and the tubuline protein for exchange inside. <\/span><\/span><\/span><\/span><\/p>\n<blockquote><p><strong><em><span style=\"color: #000000;\"><span style=\"font-family: Liberation Serif, serif;\"><span style=\"font-size: x-large;\"><span lang=\"en-US\">This remarkable cytoskeleton was probably at the beginning of <\/span><span lang=\"en-US\">the<\/span><span lang=\"en-US\"> development <\/span><span lang=\"en-US\">of the eukaryotic cell,<\/span><\/span><\/span><\/span><\/em><\/strong><\/p><\/blockquote>\n<p><span style=\"color: #000000;\"><span style=\"font-family: Liberation Serif, serif;\"><span style=\"font-size: x-large;\"><span lang=\"en-US\">says <\/span><strong><span lang=\"en-US\">Jingwei\u00a0Xu<\/span><\/strong><span lang=\"en-US\"> of the University of Zurich<\/span><\/span><\/span><\/span><\/p>\n<p><span style=\"color: #000000;\"><span style=\"font-family: Liberation Serif, serif;\"><span style=\"font-size: x-large;\"><span lang=\"en-US\">The significance of the newly published study lies in its ability to establish a foundation for future research, potentially leading to solutions for increasingly disrupted evolutionary mechanisms. How might this be achieved? One possibility is to integrate chemical and biological processes that are influenced by their underlying strengths. However, this is merely a speculative suggestion.<\/span><\/span><\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Photo: Mitochondrium, SkieTheAce, Pixabay Does evolution know the paths of the past and future? That\u2019s possible according to new research published in ,,Cell\u201d. How? By tracking the transport of signals and nutrients inside a cell. The mitochondrion is a cell organelle with a separate from the cell nucleus genetic material inherited only from a female [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[5,4,10,1,6],"tags":[],"class_list":["post-813","post","type-post","status-publish","format-standard","hentry","category-evolution-in-a-nutshell","category-genetics","category-health-security-in-a-nutshell","category-healthmedical-security","category-medicine-in-a-nutshell"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/evolutionandsecurity.com\/index.php?rest_route=\/wp\/v2\/posts\/813","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/evolutionandsecurity.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/evolutionandsecurity.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/evolutionandsecurity.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/evolutionandsecurity.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=813"}],"version-history":[{"count":2,"href":"https:\/\/evolutionandsecurity.com\/index.php?rest_route=\/wp\/v2\/posts\/813\/revisions"}],"predecessor-version":[{"id":816,"href":"https:\/\/evolutionandsecurity.com\/index.php?rest_route=\/wp\/v2\/posts\/813\/revisions\/816"}],"wp:attachment":[{"href":"https:\/\/evolutionandsecurity.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=813"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/evolutionandsecurity.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=813"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/evolutionandsecurity.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=813"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}